The Associate Director, Clinical Biomarker Lead will lead and/or contribute to the clinical asset biomarker strategy within early and late-stage clinical development programs to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient selection.

Job responsibilities include:

• Lead and/or contribute to clinical asset biomarker strategy within early and late-stage clinical development programs to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient selection.
• Represent Clinical Biomarker team at Clinical Matrix Teams (CMT) and clinical trial study teams (ST). As part of the CMT and clinical ST, establishing clear decision-making criteria to enable biomarker-informed clinical decisions.
• Develop and implement novel biomarker assays with robust assay validation.
• Provide input to clinical teams on biomarker-related elements of clinical protocols, lab manuals and consent forms.
• Provide scientific expertise and technical guidance to enable timely biomarker sample collection and analysis including from high dimensional assays.
• Execute sample testing plan and deliver high quality biomarker data packages to inform clinical development and regulatory strategy.
• Lead writing of reports to support study teams and regulatory submissions as well as contribute to publications
• Point of contact for resolving study biomarker issues.
• Collaborate with clinical operations and sample management to ensure biomarker testing and data generation
• Align with the companion diagnostics team to deliver novel precision medicine approaches to select patients for treatment.
• Serve as a point of contact for external vendors and collaborators in support of data generation
• Provide frequent project status updates related to biomarker deliverables

 Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Ph.D. with 2+ years or MA/MS with 5+ years of experience in the pharmaceutical industry setting in the application of biomarkers in clinical trials preferably in Respiratory and Immunology disease areas.
• Experience in contributions to biomarker discovery and/or assay development
• Experience in conducting biomarker analyses on various clinical sample types and working as part of a clinical study team

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Experience in managing research collaborations, contract laboratories and budgets. 
• Demonstrated scientific capability as evidenced by publications, research reports, and external presentations.
• Correlative Science Experience
• Effective verbal and written communication skills relating to colleagues and associates both inside and outside the corporation
• Flexibility to work on multiple projects as the portfolio evolves over time.
• Up to date knowledge and deep understanding of major molecular and genomic assay technologies and platforms
• Experience with clinical flow cytometry, immunohistochemistry and/or immunoassay development
• Knowledge and track-record of working to GCP principles
• Having a strong sense of urgency and excellent skills in prioritization, planning as well as timely execution in a very fast-paced environment
• Strong interpersonal and communication skills as well as ability to thrive in a matrix environment.

*LI-GSK

Why Us?

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Ukdiversity.recruitment@gsk.com or 0808 234 4391. 

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.  Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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